If you know anything about cannabis, you likely know what a cannabinoid is and you also likely know about the cannabinoids THC and CBD. However, cannabis has over 100 cannabinoids and 400 compounds, so scientists have barely scratched the surface in uncovering all their great properties.
What is cannabicitran?
Have you heard of cannabicitran (CBT)? It is one of the minor cannabinoids found in the cannabis Sativa plant. The first online reference to CBT was back in 1970 when a chemist used normal-phase flash chromatography to isolate CBG from a CBD-rich hemp distillate.
Since this type of chromatography could separate CBG from all the other cannabinoids, this got him thinking, and he then used reversed-phase flash chromatography to separate and collect other cannabinoid compounds like cannabinol (CBN), cannabichromene (CBC), cannabicyclol (CBL), and cannabicitran (CBT).
Later in 2011, CBT was first mentioned in a journal publication when Japanese scientists investigated pollen collected from male Cannabis sativa L. plants and identified 16 cannabinoids in the extract using the more modern chromatography methods of GC-FID (gas chromatography with flame ionization detector) and GC-MS (gas chromatography-mass spectrometry). Cannabicitran was one of the 16 compounds they identified.
These researchers also isolated CBT from the Chinese medicinal plant Rhododendron Anthopogonoides, which is used extensively in southern China to treat bronchitis and other respiratory ailments. Their chemical analysis of the plant extract also revealed several flavonoids, essential oils, terpenes, and tannins.
The different types of cannabinoids
Cannabinoids are generally categorized as:
- Naturally occurring plant cannabinoids called Phytocannabinoids
- Endocannabinoids that naturally occur in humans (anandamide and adrenaline are examples) and
- Synthetic cannabinoids that are manufactured in a laboratory to act similarly to phytocannabinoids and endocannabinoids.
Regardless of which of the three classes a cannabinoid falls into, all three do act on the cannabinoid receptors which are prominent in the brain, immune system, gut, and other body organs. While CB1 and CB2 receptors are widely known, many more types of receptors exist. In fact, CBD and THC are known to interact with over 50 different receptors. All of these receptors function to restore the body’s balance, called homeostasis.
The Process of chromatography
Today, Cloud Chromatography makes broad-spectrum tailored cannabinoid extracts to enhance your cannabis and hemp experience. Our lifeblood business involves characterizing and purifying new cannabinoids to bring you new products.
Chromatography is the science of separating and isolating chemical compounds, and we use this technology to select specific cannabinoids. CBT is a minor cannabinoid that occurs at between 1 and 5 percent in hemp distillate. We then concentrate them higher than levels found in any cannabis flower. We have experimented with concentrations ranging from 60 to 94% and have settled on a full-spectrum concentration of 70% CBT in a highly unique extract available in 30 ml bottles in either 150mg or 500mg concentrations. Our unique extraction process preserves the natural hemp terpenes, so our products are full-spectrum, containing a high terpene concentration. In our chemical analyses, we have determined CBT to be particularly lipophilic, so we use MCT coconut oil as a carrier oil.
We also offer a CBT/CBD extract in a 1:1 CBD: CBT ratio to give you a solid concentration of CBD as well as CBT for a daily source of cannabinoids. For example, our 1000mg drops are made with 500mg CBT and 500mg CBD.
The cannabinoids in this bottle are activated, therefore they are ready to be added to any food or drink or taken alone.
We are dedicated to bringing you new cannabinoids, and trying our CBT products is the perfect way to explore all the possibilities with this plant. CBD and THC may be the better-known cannabinoids, but we can’t wait to see scientists unlock the secrets of minor cannabinoids like CBT.